5PB3
Crystal Structure of Factor VIIa in complex with 1-[[3-[4-(5-amino-1H-pyrrolo[3,2-b]pyridin-2-yl)-5-hydroxypyrazol-1-yl]phenyl]methyl]-3-phenylurea
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Coagulation factor VII light chain | polymer | 64 | 6984.9 | 1 | UniProt (P08709) Pfam (PF14670) | Homo sapiens (Human) | Proconvertin,Serum prothrombin conversion accelerator,SPCA |
| 2 | B (C) | Coagulation factor VII heavy chain | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) | Homo sapiens (Human) | Proconvertin,Serum prothrombin conversion accelerator,SPCA |
| 3 | C, K (A, C) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | D, E, L (A, C) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | F (C) | N-({3-[4-(5-amino-1H-pyrrolo[3,2-b]pyridin-2-yl)-5-hydroxy-1H-pyrazol-1-yl]phenyl}methyl)-N'-phenylurea | non-polymer | 439.5 | 1 | Chemie (9S1) | |||
| 6 | G (C) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 7 | H, I, J (C) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 8 | M, N (A, C) | water | water | 18.0 | 348 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35088.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1054.3 | |
| All* | Total formula weight | 36142.5 |
