5P9K
CRYSTAL STRUCTURE OF BTK with CNX 774
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Tyrosine-protein kinase BTK | polymer | 279 | 32326.1 | 1 | UniProt (Q06187) Pfam (PF07714) In PDB | Homo sapiens (Human) | Agammaglobulinemia tyrosine kinase,ATK,B-cell progenitor kinase,BPK,Bruton tyrosine kinase |
2 | A | 4-[4-[[5-fluoranyl-4-[[3-(propanoylamino)phenyl]amino]pyrimidin-2-yl]amino]phenoxy]-~{N}-methyl-pyridine-2-carboxamide | non-polymer | 501.5 | 1 | Chemie (7G8) | |||
3 | water | water | 18.0 | 381 | Chemie (HOH) |
Sequence modifications
A: 382 - 659 (UniProt: Q06187)
PDB | External Database | Details |
---|---|---|
Gly 381 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 32326.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 501.5 | |
All* | Total formula weight | 32827.6 |