5OY4
GSK3beta complex with N-(6-(3,4-dihydroxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)acetamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Glycogen synthase kinase-3 beta | polymer | 420 | 46881.2 | 2 | UniProt (P49841) Pfam (PF00069) In PDB | Homo sapiens (Human) | GSK-3 beta,Serine/threonine-protein kinase GSK3B |
| 2 | X, Y | Proto-oncogene FRAT1 | polymer | 279 | 29130.0 | 2 | UniProt (Q92837) Pfam (PF05350) In PDB | Homo sapiens | Frequently rearranged in advanced T-cell lymphomas 1,FRAT-1 |
| 3 | A, B | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | A, B | ~{N}-[6-[3,4-bis(oxidanyl)phenyl]-1~{H}-pyrazolo[3,4-b]pyridin-3-yl]ethanamide | non-polymer | 284.3 | 2 | Chemie (B4K) | |||
| 5 | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 152022.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 952.8 | |
| All* | Total formula weight | 152975.1 |
