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5OY4

GSK3beta complex with N-(6-(3,4-dihydroxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)acetamide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Glycogen synthase kinase-3 betapolymer42046881.22UniProt (P49841)
Pfam (PF00069)
Homo sapiens (Human)GSK-3 beta,Serine/threonine-protein kinase GSK3B
2C, D
(X, Y)
Proto-oncogene FRAT1polymer27929130.02UniProt (Q92837)
Pfam (PF05350)
Homo sapiensFrequently rearranged in advanced T-cell lymphomas 1,FRAT-1
3E, F, G, I
(A, B)
SULFATE IONnon-polymer96.14Chemie (SO4)
4H, J
(A, B)
~{N}-[6-[3,4-bis(oxidanyl)phenyl]-1~{H}-pyrazolo[3,4-b]pyridin-3-yl]ethanamidenon-polymer284.32Chemie (B4K)
5K, L
(A, B)
waterwater18.06Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight152022.3
Non-Polymers*Number of molecules6
Total formula weight952.8
All*Total formula weight152975.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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