5OWC
Indole-2 carboxamides as selective secreted phospholipase A2 type X (sPLA2-X) inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Group 10 secretory phospholipase A2 | polymer | 122 | 13529.4 | 2 | UniProt (O15496) Pfam (PF00068) | Homo sapiens (Human) | Group X secretory phospholipase A2,sPLA2-X,Phosphatidylcholine 2-acylhydrolase 10 |
| 2 | C, K (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 3 | D, L (A, B) | 3-[3-[2-aminocarbonyl-6-(trifluoromethyloxy)indol-1-yl]phenyl]propanoic acid | non-polymer | 392.3 | 2 | Chemie (AYZ) | |||
| 4 | E, F, M, N (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 4 | Chemie (DMS) | |||
| 5 | G, H, I, J, O... (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 6 | Chemie (PEG) | |||
| 6 | Q, R (A, B) | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27058.9 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1814.1 | |
| All* | Total formula weight | 28873.0 |
