5OW8
Indole-2 carboxamides as selective secreted phospholipase A2 type X (sPLA2-X) inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Group 10 secretory phospholipase A2 | polymer | 123 | 13644.5 | 2 | UniProt (O15496) Pfam (PF00068) | Homo sapiens (Human) | Group X secretory phospholipase A2,sPLA2-X,Phosphatidylcholine 2-acylhydrolase 10 |
| 2 | C, O (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 3 | D, E, F, G, P... (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 8 | Chemie (DMS) | |||
| 4 | H, T (A, B) | 1-[3-(trifluoromethyl)phenyl]indole-2-carboxamide | non-polymer | 304.3 | 2 | Chemie (AYN) | |||
| 5 | I, J, K, L, U (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) | |||
| 6 | M, N, V, W (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 7 | X, Y (A, B) | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27289.1 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 1986.2 | |
| All* | Total formula weight | 29275.2 |
