5OVD
Ras guanine nucleotide exchange factor SOS1 (Rem-cdc25) in new crystal form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Son of sevenless homolog 1 | polymer | 490 | 57376.6 | 1 | UniProt (Q07889) Pfam (PF00618) Pfam (PF00617) | Homo sapiens (Human) | SOS-1 |
| 2 | B, C, D, E, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 3 | G (A) | water | water | 18.0 | 344 | Chemie (HOH) |
Sequence modifications
A: 560 - 1049 (UniProt: Q07889)
| PDB | External Database | Details |
|---|---|---|
| Gly 560 | Gln 560 | engineered mutation |
| Ala 561 | Glu 561 | engineered mutation |
| Met 562 | Glu 562 | engineered mutation |
| Ala 563 | Lys 563 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 57376.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 310.3 | |
| All* | Total formula weight | 57687.0 |
