5OUL
The crystal structure of CK2alpha in complex with compound 9
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Casein kinase II subunit alpha | polymer | 342 | 40786.4 | 1 | UniProt (P68400) Pfam (PF00069) In PDB | Homo sapiens (Human) | CK II alpha |
2 | A | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
3 | A | [3-chloranyl-4-(3-fluorophenyl)phenyl]methanamine | non-polymer | 235.7 | 6 | Chemie (AWE) | |||
4 | A | trifluoroacetic acid | non-polymer | 114.0 | 1 | Chemie (TFA) | |||
5 | water | water | 18.0 | 250 | Chemie (HOH) |
Sequence modifications
A: 2 - 329 (UniProt: P68400)
PDB | External Database | Details |
---|---|---|
Ser 21 | Arg 21 | engineered mutation |
Ala 74 | Lys 74 | engineered mutation |
Ala 75 | Lys 75 | engineered mutation |
Ala 76 | Lys 76 | engineered mutation |
Arg 330 | - | expression tag |
Glu 331 | - | expression tag |
Ala 332 | - | expression tag |
Met 333 | - | expression tag |
Glu 334 | - | expression tag |
His 335 | - | expression tag |
Pro 336 | - | expression tag |
Tyr 337 | - | expression tag |
Phe 338 | - | expression tag |
Tyr 339 | - | expression tag |
Thr 340 | - | expression tag |
Val 341 | - | expression tag |
Val 342 | - | expression tag |
Lys 343 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 40786.4 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1646.2 | |
All* | Total formula weight | 42432.6 |