5OS7
The crystal structure of CK2alpha in complex with compound 4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Casein kinase II subunit alpha | polymer | 352 | 41467.8 | 2 | UniProt (P68400) Pfam (PF00069) | Homo sapiens (Human) | CK II alpha |
| 2 | C, F, G, H (B, A) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 3 | D, I, J (B, A) | [3-chloranyl-4-(2-propan-2-ylphenyl)phenyl]methylazanium | non-polymer | 260.8 | 3 | Chemie (A8Q) | |||
| 4 | E, K (B, A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 5 | L, M (B, A) | water | water | 18.0 | 405 | Chemie (HOH) |
Sequence modifications
B, A: 2 - 329 (UniProt: P68400)
| PDB | External Database | Details |
|---|---|---|
| Gly -22 | - | expression tag |
| Ser -21 | - | expression tag |
| Met -20 | - | expression tag |
| Asp -19 | - | expression tag |
| Ile -18 | - | expression tag |
| Glu -17 | - | expression tag |
| Phe -16 | - | expression tag |
| Asp -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Ala -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Asp -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Ser -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Ser 21 | Arg 21 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82935.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2032.9 | |
| All* | Total formula weight | 84968.5 |
