5OQI
Crystal Structure of a disulfide trapped single chain trimer composed of the MHC I heavy chain H-2Kb Y84C E63A mutant, beta-2microglobulin, and ovalbumin-derived peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Beta-2-microglobulin,H-2 class I histocompatibility antigen, K-B alpha chain | polymer | 431 | 48123.6 | 2 | UniProt (P01887) UniProt (P01901) Pfam (PF07654) Pfam (PF00129) In PDB | Mus musculus (Mouse) | H-2K(B) |
2 | water | water | 18.0 | 369 | Chemie (HOH) |
Sequence modifications
A, B: 24 - 122 (UniProt: P01887)
A, B: 143 - 425 (UniProt: P01901)
PDB | External Database | Details |
---|---|---|
Ser 1 | - | expression tag |
Ile 2 | - | expression tag |
Ile 3 | - | expression tag |
Asn 4 | - | expression tag |
Phe 5 | - | expression tag |
Glu 6 | - | expression tag |
Lys 7 | - | expression tag |
Leu 8 | - | expression tag |
Gly 9 | - | expression tag |
Cys 10 | - | expression tag |
Gly 11 | - | expression tag |
Ala 12 | - | expression tag |
Ser 13 | - | expression tag |
Gly | - | expression tag |
Gly | - | expression tag |
Gly | - | expression tag |
Gly | - | expression tag |
Ser | - | expression tag |
Gly | - | expression tag |
Gly | - | expression tag |
Gly | - | expression tag |
Gly | - | expression tag |
Ser | - | expression tag |
Gly | - | linker |
Gly | - | linker |
Gly | - | linker |
Gly | - | linker |
Ser | - | linker |
Gly | - | linker |
Gly | - | linker |
Gly | - | linker |
Gly | - | linker |
Ser | - | linker |
Gly | - | linker |
Gly | - | linker |
Gly | - | linker |
Gly | - | linker |
Ser | - | linker |
Gly | - | linker |
Gly | - | linker |
Gly | - | linker |
Gly | - | linker |
Ser | - | linker |
PDB | External Database | Details |
---|---|---|
Ala 205 | Glu 84 | engineered mutation |
Cys 226 | Tyr 105 | engineered mutation |
His 426 | - | expression tag |
His 427 | - | expression tag |
His 428 | - | expression tag |
His 429 | - | expression tag |
His 430 | - | expression tag |
His 431 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 96247.1 | |
All* | Total formula weight | 96247.1 |