5ONR
Alzheimer's Amyloid-Beta Peptide Fragment 1-40 in Complex with Thermolysin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thermolysin | polymer | 316 | 34360.3 | 1 | UniProt (P00800) Pfam (PF01447) Pfam (PF02868) | Bacillus thermoproteolyticus | Thermostable neutral proteinase |
| 2 | B (B) | Amyloid-beta A4 protein | polymer | 3 | 301.4 | 1 | UniProt (by SIFTS) (P05067) | Homo sapiens | ABPP,APPI,APP,Alzheimer disease amyloid protein,Amyloid precursor protein,Amyloid-beta precursor protein,Cerebral vascular amyloid peptide,CVAP,PreA4,Protease nexin-II,PN-II |
| 3 | C, D, E, F (A) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | G (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | H (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | I, J (A, B) | water | water | 18.0 | 369 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34661.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 303.9 | |
| All* | Total formula weight | 34965.6 |
