5ONG
X-Ray crystal structure of a nucleosome core particle with its DNA site-specifically crosslinked to the histone octamer
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | I | DNA (147-MER) | polymer | 147 | 45430.1 | 1 | Homo sapiens (Human) | ||
2 | J | DNA (147-MER) | polymer | 147 | 45421.1 | 1 | Homo sapiens (Human) | ||
3 | A, E | Histone H3.2 | polymer | 135 | 15217.8 | 2 | UniProt (P84233) Pfam (PF00125) In PDB | Xenopus laevis (African clawed frog) | |
4 | B, F | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62799) Pfam (PF15511) In PDB | Xenopus laevis (African clawed frog) | |
5 | C, G | Histone H2A | polymer | 129 | 13978.2 | 2 | UniProt (Q6AZJ8) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P06897) In PDB | Xenopus laevis (African clawed frog) | |
6 | D, H | Histone H2B 1.1 | polymer | 122 | 13524.8 | 2 | UniProt (P02281) Pfam (PF00125) In PDB | Xenopus laevis (African clawed frog) | H2B1.1 |
7 | J, E, I | MANGANESE (II) ION | non-polymer | 54.9 | 20 | Chemie (MN) | |||
8 | A, D, E, G | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
9 | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence modifications
A, E: 1 - 135 (UniProt: P84233)
D, H: 1 - 122 (UniProt: P02281)
PDB | External Database | Details |
---|---|---|
Cys 40 | Arg 41 | engineered mutation |
Ala 102 | Gly 103 | conflict |
Ala 110 | Cys 111 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Thr 29 | Ser 33 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 10 |
Total formula weight | 199081.7 | |
Non-Polymers* | Number of molecules | 24 |
Total formula weight | 1240.6 | |
All* | Total formula weight | 200322.3 |