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5OMH

p38alpha in complex with pyrazolobenzothiazine inhibitor COXH11

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Mitogen-activated protein kinase 14polymer36041343.21UniProt (Q16539)
Pfam (PF00069)
Homo sapiens (Human)MAPK 14,Cytokine suppressive anti-inflammatory drug-binding protein,CSBP,MAP kinase MXI2,MAX-interacting protein 2,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha,Stress-activated protein kinase 2a,SAPK2a
2B
(A)
1-(3-chlorophenyl)-3-methyl-4~{H}-pyrazolo[4,3-c][1,2]benzothiazine 5,5-dioxidenon-polymer345.81Chemie (9Y5)
3C
(A)
waterwater18.07Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41343.2
Non-Polymers*Number of molecules1
Total formula weight345.8
All*Total formula weight41689.0
*Water molecules are not included.

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PDB entries from 2025-06-25

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