5OIR
InhA (T2A mutant) complexed with 2,6-Dimethyl-3-(1-(pyrimidin-2-yl)piperidin-4-yl)pyridin-4(1H)-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Enoyl-[acyl-carrier-protein] reductase [NADH] | polymer | 269 | 28524.8 | 1 | UniProt (P9WGR1) Pfam (PF13561) | Mycobacterium tuberculosis | Enoyl-ACP reductase,FAS-II enoyl-ACP reductase,NADH-dependent 2-trans-enoyl-ACP reductase |
| 2 | B (A) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 1 | Chemie (NAD) | |||
| 3 | C (A) | 2,6-dimethyl-3-(1-pyrimidin-2-ylpiperidin-4-yl)-1~{H}-pyridin-4-one | non-polymer | 284.4 | 1 | Chemie (9W8) | |||
| 4 | D, E, F, G (A) | 2-ETHOXYETHANOL | non-polymer | 90.1 | 4 | Chemie (ETX) | |||
| 5 | H (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | I (A) | water | water | 18.0 | 353 | Chemie (HOH) |
Sequence modifications
A: 3 - 269 (UniProt: P9WGR1)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ala 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28524.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1404.3 | |
| All* | Total formula weight | 29929.1 |
