5OIO
InhA (T2A mutant) complexed with 5-((3,5-dimethyl-1H-pyrazol-1-yl)methyl)-N-ethyl-1,3,4-thiadiazol-2-amine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Enoyl-[acyl-carrier-protein] reductase [NADH] | polymer | 269 | 28524.8 | 2 | UniProt (P9WGR1) Pfam (PF13561) | Mycobacterium tuberculosis | Enoyl-ACP reductase,FAS-II enoyl-ACP reductase,NADH-dependent 2-trans-enoyl-ACP reductase |
| 2 | C, E (A, B) | 5-[(3,5-dimethylpyrazol-1-yl)methyl]-~{N}-ethyl-1,3,4-thiadiazol-2-amine | non-polymer | 237.3 | 2 | Chemie (9VT) | |||
| 3 | D, F (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 321 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 269 (UniProt: P9WGR1)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ala 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57049.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1801.5 | |
| All* | Total formula weight | 58851.0 |
