5OIN
InhA (T2A mutant) complexed with N-(1-(pyrimidin-2-yl)piperidin-4-yl)acetamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Enoyl-[acyl-carrier-protein] reductase [NADH] | polymer | 269 | 28524.8 | 4 | UniProt (P9WGR1) Pfam (PF13561) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Enoyl-ACP reductase,FAS-II enoyl-ACP reductase,NADH-dependent 2-trans-enoyl-ACP reductase |
| 2 | E, G, I, K (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | F, H, J (B, C, D) | ~{N}-(1-pyrimidin-2-ylpiperidin-4-yl)ethanamide | non-polymer | 220.3 | 3 | Chemie (9W2) | |||
| 4 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 77 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 269 (UniProt: P9WGR1)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | Thr 2 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 114099.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 3314.5 | |
| All* | Total formula weight | 117413.5 |
