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5OFY

Crystal structure of the D183N variant of human Alanine:Glyoxylate Aminotransferase major allele (AGT-Ma) at pH 9.0. 2.8 Ang; internal aldimine with PLP in the active site

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine--pyruvate aminotransferasepolymer39243061.91UniProt (P21549)
Pfam (PF00266)
Homo sapiens (Human)SPT,Alanine--glyoxylate aminotransferase,AGT
2B
(A)
PYRIDOXAL-5'-PHOSPHATEnon-polymer247.11Chemie (PLP)
3C
(A)
1,4-DIETHYLENE DIOXIDEnon-polymer88.11Chemie (DIO)
4D
(A)
waterwater18.029Chemie (HOH)
Sequence modifications
A: 1 - 392 (UniProt: P21549)
PDBExternal DatabaseDetails
Asn 183Asp 183variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight43061.9
Non-Polymers*Number of molecules2
Total formula weight335.2
All*Total formula weight43397.1
*Water molecules are not included.

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PDB entries from 2025-12-24

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