5OFM
Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 5-amino-1-methyl-1H-indole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | D-3-phosphoglycerate dehydrogenase | polymer | 223 | 23933.7 | 2 | UniProt (O43175) Pfam (PF00389) Pfam (PF02826) | Homo sapiens (Human) | 3-PGDH,2-oxoglutarate reductase,Malate dehydrogenase |
| 2 | C, D (B, A) | 1-methylindol-5-amine | non-polymer | 146.2 | 2 | Chemie (9TT) | |||
| 3 | E, F (B, A) | water | water | 18.0 | 305 | Chemie (HOH) |
Sequence modifications
B, A: 94 - 315 (UniProt: O43175)
| PDB | External Database | Details |
|---|---|---|
| Met 93 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47867.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 292.4 | |
| All* | Total formula weight | 48159.7 |
