5OEP
Mycobacterium tuberculosis DprE1 in complex with inhibitor TCA481
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Decaprenylphosphoryl-beta-D-ribose oxidase | polymer | 477 | 52039.8 | 2 | UniProt (P9WJF1) Pfam (PF01565) Pfam (PF04030) In PDB | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Decaprenylphospho-beta-D-ribofuranose 2-dehydrogenase,Decaprenylphosphoryl-beta-D-ribofuranose 2'-epimerase subunit DprE1,Decaprenyl-phosphoribose 2'-epimerase subunit 1,Decaprenylphosphoryl-beta-D-ribofuranose 2'-oxidase,Decaprenylphosphoryl-beta-D-ribose 2-epimerase flavoprotein subunit,FAD-dependent decaprenylphosphoryl-beta-D-ribofuranose 2-oxidase |
2 | A, B | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
3 | A, B | ethyl ~{N}-[2-(1,3-benzothiazol-2-ylcarbonylamino)-5-fluoranyl-thiophen-3-yl]carbonylcarbamate | non-polymer | 393.4 | 2 | Chemie (9T2) | |||
4 | A | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
5 | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 461 (UniProt: P9WJF1)
PDB | External Database | Details |
---|---|---|
Met -15 | - | initiating methionine |
Gly -14 | - | expression tag |
Ser -13 | - | expression tag |
Ser -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
Ser -5 | - | expression tag |
Gln -4 | - | expression tag |
Asp -3 | - | expression tag |
Pro -2 | - | expression tag |
Asn -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 104079.7 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 2427.0 | |
All* | Total formula weight | 106506.7 |