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5OEO

Solution structure of the complex of TRPV5(655-725) with a Calmodulin E32Q/E68Q double mutant

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Calmodulin-1polymer15016937.71UniProt (P0DP23)
Pfam (PF13499)
Homo sapiens (Human)
2B
(C)
Transient receptor potential cation channel subfamily V member 5polymer737722.21UniProt (Q9NQA5)Homo sapiens (Human)TrpV5,Calcium transport protein 2,CaT2,Epithelial calcium channel 1,ECaC1,Osm-9-like TRP channel 3,OTRPC3
3C, D
(A)
CALCIUM IONnon-polymer40.12Chemie (CA)
Sequence modifications
A: 0 - 148 (UniProt: P0DP23)
PDBExternal DatabaseDetails
Ser -1-expression tag
Gln 31Glu 32engineered mutation
Gln 67Glu 68engineered mutation
C: 655 - 725 (UniProt: Q9NQA5)
PDBExternal DatabaseDetails
Gly 653-expression tag
Ala 654-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight24659.8
Non-Polymers*Number of molecules2
Total formula weight80.2
All*Total formula weight24740.0
*Water molecules are not included.

237423

PDB entries from 2025-06-11

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