5OEO

Solution structure of the complex of TRPV5(655-725) with a Calmodulin E32Q/E68Q double mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Calmodulin-1	polymer	150	16937.7	1	UniProt (P0DP23) Pfam (PF13499) In PDB	Homo sapiens (Human)
2	C	Transient receptor potential cation channel subfamily V member 5	polymer	73	7722.2	1	UniProt (Q9NQA5) In PDB	Homo sapiens (Human)	TrpV5,Calcium transport protein 2,CaT2,Epithelial calcium channel 1,ECaC1,Osm-9-like TRP channel 3,OTRPC3
3	A	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)

Sequence modifications

A: 0 - 148 (UniProt: P0DP23)

PDB	External Database	Details
Ser -1	-	expression tag
Gln 31	Glu 32	engineered mutation
Gln 67	Glu 68	engineered mutation

C: 655 - 725 (UniProt: Q9NQA5)

PDB	External Database	Details
Gly 653	-	expression tag
Ala 654	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	24659.8
Non-Polymers*	Number of molecules	2
	Total formula weight	80.2
All*	Total formula weight	24740.0

*Water molecules are not included.