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5OEG

Molecular tweezers modulate 14-3-3 protein-protein interactions

Replaces:  4HRU
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A14-3-3 protein sigmapolymer23526485.91UniProt (P31947)
Pfam (PF00244)
In PDB
Homo sapiens (Human)Epithelial cell marker protein 1,Stratifin
2A(1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaenenon-polymer726.61Chemie (9SZ)
3ACHLORIDE IONnon-polymer35.51Chemie (CL)
4waterwater18.0130Chemie (HOH)
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDBExternal DatabaseDetails
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight26485.9
Non-Polymers*Number of molecules2
Total formula weight762.1
All*Total formula weight27248.0
*Water molecules are not included.

221051

PDB entries from 2024-06-12

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