5OCH

The crystal structure of human ABCB8 in an outward-facing state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, D	ATP-binding cassette sub-family B member 8, mitochondrial	polymer	612	66540.8	3	UniProt (Q9NUT2) Pfam (PF00664) Pfam (PF00005) In PDB	Homo sapiens (Human)	Mitochondrial ATP-binding cassette 1,M-ABC1
2	B	ATP-binding cassette sub-family B member 8, mitochondrial	polymer	612	66597.9	1	UniProt (Q9NUT2) Pfam (PF00664) Pfam (PF00005) In PDB	Homo sapiens (Human)	Mitochondrial ATP-binding cassette 1,M-ABC1
3	E	ATP-binding cassette sub-family B member 8, mitochondrial	polymer	612	66597.9	1	UniProt (Q9NUT2) Pfam (PF00664) Pfam (PF00005) In PDB	Homo sapiens (Human)	Mitochondrial ATP-binding cassette 1,M-ABC1
4	F, G	ATP-binding cassette sub-family B member 8, mitochondrial	polymer	612	66597.9	2	UniProt (Q9NUT2) Pfam (PF00664) Pfam (PF00005) In PDB	Homo sapiens (Human)	Mitochondrial ATP-binding cassette 1,M-ABC1
5	H	ATP-binding cassette sub-family B member 8, mitochondrial	polymer	612	66483.8	1	UniProt (Q9NUT2) Pfam (PF00005) Pfam (PF00664) In PDB	Homo sapiens (Human)	Mitochondrial ATP-binding cassette 1,M-ABC1
6	H, A, B, C, D...	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	8	Chemie (ADP)
7	G, H, A, B, C...	MAGNESIUM ION	non-polymer		24.3	8	Chemie (MG)
8	G, H, A, B, D...	CHOLESTEROL HEMISUCCINATE	non-polymer		486.7	7	Chemie (Y01)

Sequence modifications

A, C, D: 111 - 714 (UniProt: Q9NUT2)

PDB	External Database	Details
Met 110	-	initiating methionine
Ala 715	-	expression tag
Glu 716	-	expression tag
Asn 717	-	expression tag
Leu 718	-	expression tag
Tyr 719	-	expression tag
Phe 720	-	expression tag
Gln 721	-	expression tag

B: 111 - 714 (UniProt: Q9NUT2)

PDB	External Database	Details
Met 110	-	initiating methionine
Ala 715	-	expression tag
Glu 716	-	expression tag
Asn 717	-	expression tag
Leu 718	-	expression tag
Tyr 719	-	expression tag
Phe 720	-	expression tag
Gln 721	-	expression tag

E: 111 - 714 (UniProt: Q9NUT2)

PDB	External Database	Details
Met 110	-	initiating methionine
Ala 715	-	expression tag
Glu 716	-	expression tag
Asn 717	-	expression tag
Leu 718	-	expression tag
Tyr 719	-	expression tag
Phe 720	-	expression tag
Gln 721	-	expression tag

F, G: 111 - 714 (UniProt: Q9NUT2)

PDB	External Database	Details
Met 110	-	initiating methionine
Ala 715	-	expression tag
Glu 716	-	expression tag
Asn 717	-	expression tag
Leu 718	-	expression tag
Tyr 719	-	expression tag
Phe 720	-	expression tag
Gln 721	-	expression tag

H: 111 - 714 (UniProt: Q9NUT2)

PDB	External Database	Details
Met 110	-	initiating methionine
Ala 715	-	expression tag
Glu 716	-	expression tag
Asn 717	-	expression tag
Leu 718	-	expression tag
Tyr 719	-	expression tag
Phe 720	-	expression tag
Gln 721	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	532497.6
Non-Polymers*	Number of molecules	23
	Total formula weight	7019.1
All*	Total formula weight	539516.7

*Water molecules are not included.