5OCH
The crystal structure of human ABCB8 in an outward-facing state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, D (A, C, D) | ATP-binding cassette sub-family B member 8, mitochondrial | polymer | 612 | 66540.8 | 3 | UniProt (Q9NUT2) Pfam (PF00664) Pfam (PF00005) | Homo sapiens (Human) | Mitochondrial ATP-binding cassette 1,M-ABC1 |
| 2 | B (B) | ATP-binding cassette sub-family B member 8, mitochondrial | polymer | 612 | 66597.9 | 1 | UniProt (Q9NUT2) Pfam (PF00664) Pfam (PF00005) | Homo sapiens (Human) | Mitochondrial ATP-binding cassette 1,M-ABC1 |
| 3 | E (E) | ATP-binding cassette sub-family B member 8, mitochondrial | polymer | 612 | 66597.9 | 1 | UniProt (Q9NUT2) Pfam (PF00664) Pfam (PF00005) | Homo sapiens (Human) | Mitochondrial ATP-binding cassette 1,M-ABC1 |
| 4 | F, G (F, G) | ATP-binding cassette sub-family B member 8, mitochondrial | polymer | 612 | 66597.9 | 2 | UniProt (Q9NUT2) Pfam (PF00664) Pfam (PF00005) | Homo sapiens (Human) | Mitochondrial ATP-binding cassette 1,M-ABC1 |
| 5 | H (H) | ATP-binding cassette sub-family B member 8, mitochondrial | polymer | 612 | 66483.8 | 1 | UniProt (Q9NUT2) Pfam (PF00005) Pfam (PF00664) | Homo sapiens (Human) | Mitochondrial ATP-binding cassette 1,M-ABC1 |
| 6 | CA, I, L, O, Q... (H, A, B, C, D...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 8 | Chemie (ADP) | |||
| 7 | AA, DA, J, M, P... (G, H, A, B, C...) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 8 | BA, EA, K, N, S... (G, H, A, B, D...) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 7 | Chemie (Y01) |
Sequence modifications
A, C, D: 111 - 714 (UniProt: Q9NUT2)
B: 111 - 714 (UniProt: Q9NUT2)
E: 111 - 714 (UniProt: Q9NUT2)
F, G: 111 - 714 (UniProt: Q9NUT2)
H: 111 - 714 (UniProt: Q9NUT2)
| PDB | External Database | Details |
|---|---|---|
| Met 110 | - | initiating methionine |
| Ala 715 | - | expression tag |
| Glu 716 | - | expression tag |
| Asn 717 | - | expression tag |
| Leu 718 | - | expression tag |
| Tyr 719 | - | expression tag |
| Phe 720 | - | expression tag |
| Gln 721 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 110 | - | initiating methionine |
| Ala 715 | - | expression tag |
| Glu 716 | - | expression tag |
| Asn 717 | - | expression tag |
| Leu 718 | - | expression tag |
| Tyr 719 | - | expression tag |
| Phe 720 | - | expression tag |
| Gln 721 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 110 | - | initiating methionine |
| Ala 715 | - | expression tag |
| Glu 716 | - | expression tag |
| Asn 717 | - | expression tag |
| Leu 718 | - | expression tag |
| Tyr 719 | - | expression tag |
| Phe 720 | - | expression tag |
| Gln 721 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 110 | - | initiating methionine |
| Ala 715 | - | expression tag |
| Glu 716 | - | expression tag |
| Asn 717 | - | expression tag |
| Leu 718 | - | expression tag |
| Tyr 719 | - | expression tag |
| Phe 720 | - | expression tag |
| Gln 721 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 110 | - | initiating methionine |
| Ala 715 | - | expression tag |
| Glu 716 | - | expression tag |
| Asn 717 | - | expression tag |
| Leu 718 | - | expression tag |
| Tyr 719 | - | expression tag |
| Phe 720 | - | expression tag |
| Gln 721 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 532497.6 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 7019.1 | |
| All* | Total formula weight | 539516.7 |
