5OBJ
Aurora A kinase in complex with 2-(3-fluorophenyl)quinoline-4-carboxylic acid and ATP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Aurora kinase A | polymer | 272 | 31456.2 | 1 | UniProt (O14965) Pfam (PF00069) In PDB | Homo sapiens (Human) | Aurora 2,Aurora/IPL1-related kinase 1,hARK1,Breast tumor-amplified kinase,Serine/threonine-protein kinase 15,Serine/threonine-protein kinase 6,Serine/threonine-protein kinase aurora-A |
2 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
3 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
4 | A | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
5 | A | 2-(3-fluorophenyl)quinoline-4-carboxylic acid | non-polymer | 267.3 | 1 | Chemie (9QK) | |||
6 | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 125 - 391 (UniProt: O14965)
PDB | External Database | Details |
---|---|---|
Gly 120 | - | expression tag |
Ser 121 | - | expression tag |
Met 122 | - | expression tag |
Gly 123 | - | expression tag |
Ser 124 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 31456.2 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 919.1 | |
All* | Total formula weight | 32375.3 |