5OBH
Crystal structure of glycine binding protein in complex with bicuculline
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Soluble acetylcholine receptor | polymer | 249 | 28309.7 | 5 | UniProt (Q8WSF8) Pfam (PF02931) | Aplysia californica (California sea hare) | Glycine binding protein |
| 2 | F (F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 627.6 | 1 | In PDB BIRD (PRD_900017) GlyTouCan (G47362BJ) | triacetyl-beta-chitotriose | ||
| 3 | G, I, K, M, P (A, B, C, D, E) | (5S)-6,6-dimethyl-5-[(6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl]-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-6-ium | non-polymer | 382.4 | 5 | Chemie (J94) | |||
| 4 | H, J, L, O, R (A, B, C, D, E) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 5 | N, Q (D, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 6 | S, T, U, V, W (A, B, C, D, E) | water | water | 18.0 | 404 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 236 (UniProt: Q8WSF8)
| PDB | External Database | Details |
|---|---|---|
| Phe 53 | Thr 53 | engineered mutation |
| Val 60 | Ala 60 | conflict |
| Arg 74 | Gln 74 | engineered mutation |
| Ala 110 | Tyr 110 | engineered mutation |
| Ser 135 | Ile 135 | engineered mutation |
| Val 155 | Ala 155 | conflict |
| Glu 162 | Gly 162 | engineered mutation |
| Lys 206 | Ser 206 | engineered mutation |
| Gly 207 | Cys 207 | engineered mutation |
| Thr 208 | Cys 208 | engineered mutation |
| Gly 209 | Pro 209 | engineered mutation |
| Glu 237 | - | expression tag |
| Asn 238 | - | expression tag |
| Leu 239 | - | expression tag |
| Tyr 240 | - | expression tag |
| Phe 241 | - | expression tag |
| Gln 242 | - | expression tag |
| Gly 243 | - | expression tag |
| His 244 | - | expression tag |
| His 245 | - | expression tag |
| His 246 | - | expression tag |
| His 247 | - | expression tag |
| His 248 | - | expression tag |
| His 249 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 141548.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 627.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2531.6 | |
| All* | Total formula weight | 144707.6 |
