5OAV
High resolution crystal structure of the c-Src-SH3 domain mutant E93V in complex with the high affinity synthetic peptide APP12: monoclinic crystal
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Proto-oncogene tyrosine-protein kinase Src | polymer | 61 | 6904.6 | 2 | UniProt (P00523) Pfam (PF00018) | Gallus gallus (Chicken) | Proto-oncogene c-Src,pp60c-src,p60-Src |
| 2 | B, D (B, D) | APP12 | polymer | 13 | 1412.7 | 2 | synthetic construct | ||
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence modifications
A, C: 85 - 141 (UniProt: P00523)
| PDB | External Database | Details |
|---|---|---|
| Gly 81 | - | expression tag |
| Ser 82 | - | expression tag |
| His 83 | - | expression tag |
| Met 84 | - | expression tag |
| Val 93 | Glu 93 | engineered mutation |
| Arg 128 | Gln 128 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 16634.6 | |
| All* | Total formula weight | 16634.6 |
