5OAN

Crystal structure of mutant AChBP in complex with glycine (T53F, Q74R, Y110A, I135S, G162E, S206CCP_KGTG)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E (A, B, C, D, E)	Soluble acetylcholine receptor	polymer	249	28309.7	5	UniProt (Q8WSF8) Pfam (PF02931)	Aplysia californica (California sea hare)
2	F, I, L, O, S (A, B, C, D, E)	CHLORIDE ION	non-polymer		35.5	5	Chemie (CL)
3	G, J, M, P, Q (A, B, C, D, E)	ACETATE ION	non-polymer		59.0	5	Chemie (ACT)
4	H, K, N, R (B, C, D, E)	GLYCINE	non-polymer		75.1	4	Chemie (GLY)
5	T, U, V, W, X (A, B, C, D, E)	water	water		18.0	250	Chemie (HOH)

Sequence modifications

A, B, C, D, E: 1 - 236 (UniProt: Q8WSF8)

PDB	External Database	Details
Phe 53	Thr 53	engineered mutation
Val 60	Ala 60	engineered mutation
Arg 74	Gln 74	engineered mutation
Ala 110	Tyr 110	engineered mutation
Ser 135	Ile 135	engineered mutation
Val 155	Ala 155	engineered mutation
Glu 162	Gly 162	engineered mutation
Lys 206	Ser 206	engineered mutation
Gly 207	Cys 207	engineered mutation
Thr 208	Cys 208	engineered mutation
Gly 209	Pro 209	engineered mutation
Glu 237	-	expression tag
Asn 238	-	expression tag
Leu 239	-	expression tag
Tyr 240	-	expression tag
Phe 241	-	expression tag
Gln 242	-	expression tag
Gly 243	-	expression tag
His 244	-	expression tag
His 245	-	expression tag
His 246	-	expression tag
His 247	-	expression tag
His 248	-	expression tag
His 249	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	141548.4
Non-Polymers*	Number of molecules	14
	Total formula weight	772.8
All*	Total formula weight	142321.2

*Water molecules are not included.