5OA5
CELLOBIOHYDROLASE I (CEL7A) FROM HYPOCREA JECORINA WITH IMPROVED THERMAL STABILITY
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Exoglucanase 1 | polymer | 434 | 46262.2 | 2 | UniProt (P62694) Pfam (PF00840) | Hypocrea jecorina | 1,4-beta-cellobiohydrolase,Exocellobiohydrolase I,CBHI,Exoglucanase I |
| 2 | C, D, E, F, G... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 3 | I (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | J, K (A, B) | water | water | 18.0 | 546 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 434 (UniProt: P62694)
| PDB | External Database | Details |
|---|---|---|
| Pro 8 | Ser 25 | engineered mutation |
| Ile 41 | Thr 58 | engineered mutation |
| Ser 49 | Asn 66 | engineered mutation |
| Thr 68 | Ala 85 | engineered mutation |
| Asp 89 | Asn 106 | engineered mutation |
| Thr 92 | Ser 109 | engineered mutation |
| Asn 113 | Ser 130 | engineered mutation |
| Thr 196 | Ser 213 | engineered mutation |
| Leu 227 | Pro 244 | engineered mutation |
| Lys 249 | Asp 266 | engineered mutation |
| Pro 255 | Thr 272 | engineered mutation |
| Pro 278 | Ser 295 | engineered mutation |
| Lys 295 | Glu 312 | engineered mutation |
| Pro 296 | Thr 313 | engineered mutation |
| Tyr 332 | Thr 349 | engineered mutation |
| Asp 403 | Val 420 | engineered mutation |
| Phe 411 | Ser 428 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 92524.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1419.3 | |
| All* | Total formula weight | 93943.8 |
