5O3G
Human Brd2(BD2) mutant in complex with AL-Am1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Bromodomain-containing protein 2 | polymer | 114 | 13361.4 | 2 | UniProt (P25440) Pfam (PF00439) In PDB | Homo sapiens (Human) | O27.1.1,Really interesting new gene 3 protein |
2 | A, B | (2~{R})-2-[(4~{S})-6-(4-chlorophenyl)-8-methoxy-1-methyl-4~{H}-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-~{N}-ethyl-pent-4-enamide | non-polymer | 464.0 | 2 | Chemie (9J8) | |||
3 | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
A, B: 344 - 455 (UniProt: P25440)
PDB | External Database | Details |
---|---|---|
Ser 342 | - | expression tag |
Met 343 | - | expression tag |
Val 383 | Leu 383 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 26722.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 927.9 | |
All* | Total formula weight | 27650.7 |