5O3B
Human Brd2(BD2) mutant in complex with AL
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Bromodomain-containing protein 2 | polymer | 114 | 13361.4 | 4 | UniProt (P25440) Pfam (PF00439) In PDB | Homo sapiens (Human) | O27.1.1,Really interesting new gene 3 protein |
| 2 | A, B, C, D | methyl (2~{R})-2-[(4~{S})-6-(4-chlorophenyl)-8-methoxy-1-methyl-4~{H}-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]pent-4-enoate | non-polymer | 450.9 | 4 | Chemie (9HZ) | |||
| 3 | water | water | 18.0 | 559 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 344 - 455 (UniProt: P25440)
| PDB | External Database | Details |
|---|---|---|
| Ser 342 | - | expression tag |
| Met 343 | - | expression tag |
| Val 383 | Leu 383 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 53445.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1803.7 | |
| All* | Total formula weight | 55249.2 |
