5O38
Human Brd2(BD2) mutant in free form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain-containing protein 2 | polymer | 114 | 13361.4 | 1 | UniProt (P25440) Pfam (PF00439) In PDB | Homo sapiens (Human) | O27.1.1,Really interesting new gene 3 protein |
| 2 | A | 3-[(2~{R})-2-oxidanylpropoxy]-2-[[(2~{R})-2-oxidanylpropoxy]methyl]-2-[[(2~{S})-2-oxidanylpropoxy]methyl]propan-1-ol | non-polymer | 310.4 | 1 | Chemie (9JB) | |||
| 3 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | A | (2~{S})-1-[(2~{S})-2-oxidanylpropoxy]propan-2-ol | non-polymer | 134.2 | 1 | Chemie (DQW) | |||
| 5 | water | water | 18.0 | 237 | Chemie (HOH) |
Sequence modifications
A: 344 - 455 (UniProt: P25440)
| PDB | External Database | Details |
|---|---|---|
| Ser 342 | - | expression tag |
| Met 343 | - | expression tag |
| Val 383 | Leu 383 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13361.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 480.0 | |
| All* | Total formula weight | 13841.4 |
