5O2F
Crystal structure of NDM-1 in complex with hydrolyzed ampicillin - new refinement
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Metallo-beta-lactamase type 2 | polymer | 246 | 26045.3 | 2 | UniProt (C7C422) | Klebsiella pneumoniae | B2 metallo-beta-lactamase,Beta-lactamase type II,Metallo-beta-lactamase NDM-1,Metallo-beta-lactamase type II,New Delhi metallo-beta-lactamase-1,NDM-1 |
| 2 | C, D, L, M (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | E, N (A, B) | (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | non-polymer | 367.4 | 2 | Chemie (ZZ7) PubChem (53364402) PubChem (76967799) PubChem (76967800) PubChem (100971666) PubChem (101043514) PubChem (6453491) PubChem (6914605) PubChem (100971667) PubChem (101505298) PubChem (101543018) PubChem (11726464) PubChem (131698399) PubChem (145865052) PubChem (163410307) | |||
| 4 | F, G, H, O (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | I (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 6 | J, K, P (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 7 | Q, R (A, B) | water | water | 18.0 | 433 | Chemie (HOH) |
Sequence modifications
A, B: 29 - 270 (UniProt: C7C422)
| PDB | External Database | Details |
|---|---|---|
| Gly 25 | - | expression tag |
| Ser 26 | - | expression tag |
| His 27 | - | expression tag |
| Met 28 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52090.6 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1602.4 | |
| All* | Total formula weight | 53693.0 |
