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5O2D

PARP14 Macrodomain 2 with inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Poly [ADP-ribose] polymerase 14polymer20021593.51UniProt (Q460N5)
Pfam (PF01661)
Homo sapiens (Human)PARP-14,ADP-ribosyltransferase diphtheria toxin-like 8,ARTD8,B aggressive lymphoma protein 2
2B
(A)
~{N}-[2-(9~{H}-carbazol-1-yl)phenyl]methanesulfonamidenon-polymer336.41Chemie (9HH)
3C
(A)
waterwater18.0130Chemie (HOH)
Sequence modifications
A: 994 - 1191 (UniProt: Q460N5)
PDBExternal DatabaseDetails
Ser 992-expression tag
Met 993-expression tag
Ser 1048Lys 1048engineered mutation
Ser 1154Lys 1154engineered mutation
Ser 1158Lys 1158engineered mutation
Ser 1162Lys 1162engineered mutation
Sequence viewer
Display chain:
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight21593.5
Non-Polymers*Number of molecules1
Total formula weight336.4
All*Total formula weight21929.9
*Water molecules are not included.

239149

数据于2025-07-23公开中

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