5O1R

human Fab 5H2 bound to NHBA-C3 from Neisseria meningitidis serogroup B

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	GNA2132	polymer	127	13706.0	2	UniProt (Q9JPP1) Pfam (PF01298) In PDB	Neisseria meningitidis	Gna2132,Heparin binding protein,Neisserial heparin binding antigen,Putative lipoprotein GNA2132
2	H, I	IGH@ protein	polymer	265	27963.0	2	UniProt (Q6GMX6) Pfam (PF07686) Pfam (PF07654) In PDB	Homo sapiens (Human)
3	L, M	Uncharacterized protein	polymer	213	23094.6	2	UniProt (Q6GMX0) Pfam (PF07686) Pfam (PF07654) In PDB	Homo sapiens (Human)
4	A, H, I, M	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
5		water	water		18.0	46	Chemie (HOH)

Sequence modifications

A, B: 312 - 427 (UniProt: Q9JPP1)

PDB	External Database	Details
Met 309	-	initiating methionine
Ala 310	-	expression tag
Ser 311	-	expression tag
Leu 428	-	expression tag
Glu 429	-	expression tag
His 430	-	expression tag
His 431	-	expression tag
His 432	-	expression tag
His 433	-	expression tag
His 434	-	expression tag
His 435	-	expression tag

H, I: 1 - 228 (UniProt: Q6GMX6)

PDB	External Database	Details
Val 29	Ile 48	conflict
Ser 31	-	insertion
Gly 32	-	insertion
Ser 33	Gly 50	conflict
Ser 34	Tyr 51	conflict
Thr 37	Ser 54	conflict
Thr 42	Pro 59	conflict
Pro 43	Ala 60	conflict
Tyr 52	Arg 69	conflict
Thr 53	Ile 70	conflict
Ser 54	Tyr 71	conflict
Tyr 55	Thr 72	conflict
Lys 60	Asn 77	conflict
Leu 71	Met 88	conflict
Met 75	Thr 92	conflict
Lys 85	Ser 102	conflict
Phe 96	Tyr 113	conflict
Asp 100	Gly 117	conflict
Asp 103	-	insertion
Val 104	-	insertion
Ala 105	-	insertion
Ser 106	-	insertion
Gly 107	-	insertion
Ser 108	Thr 120	conflict
Ser 109	Tyr 121	conflict
Phe 112	Tyr 124	conflict
Arg 220	Lys 232	conflict
Gly 229	-	expression tag
Ser 230	-	expression tag
Glu 231	-	expression tag
Asn 232	-	expression tag
Leu 233	-	expression tag
Tyr 234	-	expression tag
Phe 235	-	expression tag
Gln 236	-	expression tag
Gly 237	-	expression tag
Ser 238	-	expression tag
Trp 239	-	expression tag
Ser 240	-	expression tag
His 241	-	expression tag
Pro 242	-	expression tag
Gln 243	-	expression tag
Phe 244	-	expression tag
Glu 245	-	expression tag
Lys 246	-	expression tag
Gly 247	-	expression tag
Gly 248	-	expression tag
Ser 249	-	expression tag
Gly 250	-	expression tag
Gly 251	-	expression tag
Gly 252	-	expression tag
Ser 253	-	expression tag
Gly 254	-	expression tag
Gly 255	-	expression tag
Gly 256	-	expression tag
Ser 257	-	expression tag
Trp 258	-	expression tag
Ser 259	-	expression tag
His 260	-	expression tag
Pro 261	-	expression tag
Gln 262	-	expression tag
Phe 263	-	expression tag
Glu 264	-	expression tag
Lys 265	-	expression tag

L, M: 1 - 213 (UniProt: Q6GMX0)

PDB	External Database	Details
Glu 1	Asp 23	conflict
Val 3	Gln 25	conflict
Thr 7	Ser 29	conflict
Ser 28	Asn 50	conflict
Ser 30	Asn 52	conflict
Gln 38	Leu 60	conflict
Thr 42	Lys 64	conflict
Lys 45	Asn 67	conflict
Thr 48	Ile 70	conflict
Gly 55	Gln 77	conflict
Leu 71	Phe 93	conflict
Glu 81	Asp 103	conflict
Gly 93	Asn 115	conflict
Ser 94	Ile 116	conflict
-	Leu 118	deletion
Gln 99	Gly 122	conflict
Lys 102	Asn 125	conflict
Leu 103	Val 126	conflict
Arg 106	Lys 129	conflict

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	129527.1
Non-Polymers*	Number of molecules	5
	Total formula weight	310.3
All*	Total formula weight	129837.5

*Water molecules are not included.