5NZF
Complex of H275Y/I223V mutant variant of neuraminidase from H1N1 influenza virus with oseltamivir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Neuraminidase | polymer | 388 | 42738.6 | 4 | UniProt (W5R8B8) UniProt (by SIFTS) (C3W6G3) | unidentified influenza virus | |
| 2 | E (E) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 3 | F (F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | CA, DA, G, H, L... (D, A, B, C) | CALCIUM ION | non-polymer | 40.1 | 9 | Chemie (CA) PubChem (271) | |||
| 5 | EA, I, O, X (D, A, B, C) | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | non-polymer | 284.4 | 4 | Chemie (G39) PubChem (40640967) PubChem (40640969) PubChem (40640971) PubChem (44345914) PubChem (40640973) PubChem (58753598) PubChem (71038155) PubChem (71065667) PubChem (449381) PubChem (4631786) PubChem (95162772) PubChem (121452907) PubChem (124637832) PubChem (129886749) PubChem (134694948) PubChem (137378365) | |||
| 6 | FA, GA, J, K, P... (D, A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | |||
| 7 | AA, BA, HA, IA, JA... (C, D, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 11 | Chemie (EDO) | |||
| 8 | NA (D) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 9 | OA, PA, QA, RA (A, B, C, D) | water | water | 18.0 | 1325 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 82 - 469 (UniProt: W5R8B8)
| PDB | External Database | Details |
|---|---|---|
| Val 223 | Ile 223 | conflict |
| Tyr 275 | His 275 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 170954.5 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1335.2 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 4194.7 | |
| All* | Total formula weight | 176484.5 |
