5NZF
Complex of H275Y/I223V mutant variant of neuraminidase from H1N1 influenza virus with oseltamivir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Neuraminidase | polymer | 388 | 42738.6 | 4 | UniProt (W5R8B8) Pfam (PF00064) UniProt (by SIFTS) (C3W6G3) | unidentified influenza virus | |
| 2 | E (E) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 3 | F (F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | CA, DA, G, H, L... (D, A, B, C) | CALCIUM ION | non-polymer | 40.1 | 9 | Chemie (CA) | |||
| 5 | EA, I, O, X (D, A, B, C) | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | non-polymer | 284.4 | 4 | Chemie (G39) | |||
| 6 | FA, GA, J, K, P... (D, A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | |||
| 7 | AA, BA, HA, IA, JA... (C, D, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 11 | Chemie (EDO) | |||
| 8 | NA (D) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 9 | OA, PA, QA, RA (A, B, C, D) | water | water | 18.0 | 1325 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 82 - 469 (UniProt: W5R8B8)
| PDB | External Database | Details |
|---|---|---|
| Val 223 | Ile 223 | conflict |
| Tyr 275 | His 275 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 170954.5 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1335.2 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 4194.7 | |
| All* | Total formula weight | 176484.5 |
