5NXD
LIM Domain Kinase 2 (LIMK2) In Complex With TH-300
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | LIM domain kinase 2 | polymer | 305 | 34799.7 | 2 | UniProt (P53671) Pfam (PF07714) | Homo sapiens (Human) | LIMK-2 |
| 2 | C, E (A, B) | 4-[(3-chlorophenyl)sulfamoyl]-~{N}-(phenylmethyl)-~{N}-propyl-benzamide | non-polymer | 443.0 | 2 | Chemie (9D8) | |||
| 3 | D, F (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 133 | Chemie (HOH) |
Sequence modifications
A, B: 330 - 632 (UniProt: P53671)
| PDB | External Database | Details |
|---|---|---|
| Ser 328 | - | expression tag |
| Met 329 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69599.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1010.1 | |
| All* | Total formula weight | 70609.5 |
