5NWM
Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nuclear receptor coactivator 1 | polymer | 132 | 14811.8 | 1 | UniProt (Q15788) Pfam (PF14598) | Homo sapiens (Human) | NCoA-1,Class E basic helix-loop-helix protein 74,bHLHe74,Protein Hin-2,RIP160,Renal carcinoma antigen NY-REN-52,Steroid receptor coactivator 1,SRC-1 |
| 2 | B (B) | Signal transducer and activator of transcription 6 | polymer | 32 | 3452.8 | 1 | UniProt (P42226) | Homo sapiens (Human) | IL-4 Stat |
Sequence modifications
A: 257 - 385 (UniProt: Q15788)
| PDB | External Database | Details |
|---|---|---|
| Gly 254 | - | expression tag |
| His 255 | - | expression tag |
| Met 256 | - | expression tag |
| Arg 343 | Lys 343 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 18264.6 | |
| All* | Total formula weight | 18264.6 |
