5NWH
Potent inhibitors of NUDT5 silence hormone signaling in breast cancer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ADP-sugar pyrophosphatase | polymer | 219 | 24355.6 | 2 | UniProt (Q9UKK9) Pfam (PF00293) | Homo sapiens (Human) | 8-oxo-dGDP phosphatase,Nuclear ATP-synthesis protein NUDIX5,Nucleoside diphosphate-linked moiety X motif 5,hNUDT5,YSA1H |
| 2 | C, D (A) | 7-[[5-(3,4-dichlorophenyl)-1,3,4-oxadiazol-2-yl]methyl]-1,3-dimethyl-8-piperazin-1-yl-purine-2,6-dione | non-polymer | 491.3 | 2 | Chemie (9CH) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48711.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 982.7 | |
| All* | Total formula weight | 49693.9 |
