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5NWE

Complex of H275Y mutant variant of neuraminidase from H1N1 influenza virus with oseltamivir

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Neuraminidasepolymer38842752.74UniProt (C9EKP8)
UniProt (by SIFTS) (C3W6G3)
Influenza A virus
2E
(E)
alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranosebranched894.81In PDB
GlyTouCan (G00395TQ)
3F
(F)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.41In PDB
GlyTouCan (G42666HT)
4G, H, L, M, R...
(A, B, C, D)
CALCIUM IONnon-polymer40.18Chemie (CA)
5I, N, T, Y
(A, B, C, D)
(3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acidnon-polymer284.44Chemie (G39)
6AA, BA, J, K, O...
(D, A, B, C)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.210Chemie (NAG)
7CA, DA, EA, FA
(A, B, C, D)
waterwater18.01380Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight171010.6
BranchedNumber of molecules2
Total formula weight1319.2
Non-Polymers*Number of molecules22
Total formula weight3670.1
All*Total formula weight176000.0
*Water molecules are not included.

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PDB entries from 2026-01-14

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