5NWE

Complex of H275Y mutant variant of neuraminidase from H1N1 influenza virus with oseltamivir

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Neuraminidase	polymer	388	42752.7	4	UniProt (C9EKP8) Pfam (PF00064) UniProt (by SIFTS) (C3W6G3) In PDB	Influenza A virus
2	E	alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		894.8	1	In PDB GlyTouCan (G00395TQ)
3	F	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	A, B, C, D	CALCIUM ION	non-polymer		40.1	8	Chemie (CA)
5	A, B, C, D	(3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid	non-polymer		284.4	4	Chemie (G39)
6	D, A, B, C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	10	Chemie (NAG)
7		water	water		18.0	1380	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	171010.6
Branched	Number of molecules	2
	Total formula weight	1319.2
Non-Polymers*	Number of molecules	22
	Total formula weight	3670.1
All*	Total formula weight	176000.0

*Water molecules are not included.