5NTU
Crystal Structure of human Pro-myostatin Precursor at 2.6 A Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Growth/differentiation factor 8 | polymer | 335 | 37881.3 | 2 | UniProt (O14793) Pfam (PF00688) Pfam (PF00019) In PDB | Homo sapiens (Human) | GDF-8,Myostatin |
| 2 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 21 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A, B: 43 - 375 (UniProt: O14793)
| PDB | External Database | Details |
|---|---|---|
| Gly 41 | - | expression tag |
| Ser 42 | - | expression tag |
| Ala 217 | Lys 217 | engineered mutation |
| Ala 218 | Gln 218 | engineered mutation |
| Ala 220 | Glu 220 | engineered mutation |
| Ala 319 | Gln 319 | engineered mutation |
| Ala 320 | Lys 320 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75762.7 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 1374.3 | |
| All* | Total formula weight | 77137.0 |
