5NRD
A Native Ternary Complex of Alpha-1,3-Galactosyltransferase (a-3GalT) Supports a Conserved Reaction Mechanism for Retaining Glycosyltransferases - alpha-3GalT in complex with Co2+, UDP-Gal and lactose - a3GalT-Co2+-UDP-Gal-LAT-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | N-acetyllactosaminide alpha-1,3-galactosyltransferase | polymer | 292 | 34365.5 | 2 | UniProt (P14769) Pfam (PF03414) In PDB | Bos taurus (Bovine) | UDP-galactose:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase,Galactosyltransferase |
| 2 | C | beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900004) GlyTouCan (G84224TW) | beta-lactose | ||
| 3 | A, B | COBALT (II) ION | non-polymer | 58.9 | 2 | Chemie (CO) | |||
| 4 | A, B | GALACTOSE-URIDINE-5'-DIPHOSPHATE | non-polymer | 566.3 | 2 | Chemie (GDU) | |||
| 5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence modifications
A, B: 80 - 368 (UniProt: P14769)
| PDB | External Database | Details |
|---|---|---|
| Gly 77 | - | expression tag |
| Ser 78 | - | expression tag |
| Met 79 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68731.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1342.6 | |
| All* | Total formula weight | 70415.8 |
