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5NNF

Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated BAZ1B peptide (K221ac)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Bromodomain-containing protein 4polymer12715099.41UniProt (O60885)
Pfam (PF00439)
Homo sapiens (Human)Protein HUNK1
2B
(B)
FLPH(ALY)YDVKLpolymer101303.51UniProt (by SIFTS) (Q9UIG0)Homo sapiens
3C, D
(A, B)
waterwater18.0209Chemie (HOH)
Sequence modifications
A: 44 - 168 (UniProt: O60885)
PDBExternal DatabaseDetails
Ser 42-expression tag
Met 43-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight16402.9
All*Total formula weight16402.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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