5NMX

Crystal Structure of the pyrrolizidine alkaloid N-oxygenase from Zonocerus variegatus in complex with FAD and NADP+

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Flavin-containing monooxygenase	polymer	425	49299.1	4	UniProt (L0N8S9) Pfam (PF00743)	Zonocerus variegatus
2	E, G, J, M (A, B, C, D)	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	4	Chemie (FAD)
3	F, H, K, N (A, B, C, D)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	4	Chemie (NAP)
4	I, L, O (B, C, D)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
5	P, Q, R, S (A, B, C, D)	water	water		18.0	1572	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 413 (UniProt: L0N8S9)

PDB	External Database	Details
Tyr 414	-	expression tag
Ala 415	-	expression tag
Ala 416	-	expression tag
Ala 417	-	expression tag
Leu 418	-	expression tag
Glu 419	-	expression tag
His 420	-	expression tag
His 421	-	expression tag
His 422	-	expression tag
His 423	-	expression tag
His 424	-	expression tag
His 425	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	197196.2
Non-Polymers*	Number of molecules	11
	Total formula weight	6188.7
All*	Total formula weight	203384.9

*Water molecules are not included.