5NJX

Human FKBP51 protein in complex with C-terminal peptide of Human HSP 90-alpha

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Peptidyl-prolyl cis-trans isomerase FKBP5	polymer	462	51701.6	1	UniProt (Q13451) Pfam (PF00254) Pfam (PF00515)	Homo sapiens (Human)	PPIase FKBP5,51 kDa FK506-binding protein,FKBP-51,54 kDa progesterone receptor-associated immunophilin,Androgen-regulated protein 6,FF1 antigen,FK506-binding protein 5,FKBP-5,FKBP54,p54,HSP90-binding immunophilin,Rotamase
2	B (B)	HSP90AA1 protein	polymer	16	2026.1	1	UniProt (Q96HX7)	Homo sapiens
3	C, D, E (A)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
4	F, G (A, B)	water	water		18.0	175	Chemie (HOH)

Sequence modifications

A: 1 - 457 (UniProt: Q13451)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

B: 723 - 732 (UniProt: Q96HX7)

PDB	External Database	Details
His 717	-	expression tag
His 718	-	expression tag
His 719	-	expression tag
His 720	-	expression tag
His 721	-	expression tag
His 722	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	53727.7
Non-Polymers*	Number of molecules	3
	Total formula weight	288.2
All*	Total formula weight	54015.9

*Water molecules are not included.