5NIB
Ligand complex of RORg LBD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nuclear receptor ROR-gamma | polymer | 288 | 33255.1 | 1 | UniProt (P51449) Pfam (PF00104) | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
| 2 | B (C) | The tethered SRC2-2 peptide | polymer | 15 | 1838.2 | 1 | UniProt (by SIFTS) (Q15596) | Homo sapiens | |
| 3 | C (A) | ~{N}-[4-[2-[(3-cyanophenyl)methoxy]pyridin-3-yl]thiophen-2-yl]-2-(4-ethylsulfonylphenyl)ethanamide | non-polymer | 517.6 | 1 | Chemie (8Y5) | |||
| 4 | D (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | E (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | F, G (A, C) | water | water | 18.0 | 176 | Chemie (HOH) |
Sequence modifications
A: 265 - 507 (UniProt: P51449)
| PDB | External Database | Details |
|---|---|---|
| Met 243 | - | initiating methionine |
| His 244 | - | expression tag |
| Asn 245 | - | expression tag |
| His 246 | - | expression tag |
| Asn 247 | - | expression tag |
| His 248 | - | expression tag |
| Asn 249 | - | expression tag |
| His 250 | - | expression tag |
| Asn 251 | - | expression tag |
| His 252 | - | expression tag |
| Asn 253 | - | expression tag |
| His 254 | - | expression tag |
| Asn 255 | - | expression tag |
| Gly 256 | - | expression tag |
| Gly 257 | - | expression tag |
| Glu 258 | - | expression tag |
| Asn 259 | - | expression tag |
| Leu 260 | - | expression tag |
| Tyr 261 | - | expression tag |
| Phe 262 | - | expression tag |
| Gln 263 | - | expression tag |
| Gly 264 | - | expression tag |
| Gly 508 | - | expression tag |
| Gly 509 | - | expression tag |
| Ser 510 | - | expression tag |
| Gly 511 | - | expression tag |
| Gly 512 | - | expression tag |
| Ser 513 | - | expression tag |
| Gly 514 | - | expression tag |
| Gly 515 | - | expression tag |
| Lys 516 | - | expression tag |
| Glu 517 | - | expression tag |
| Lys 518 | - | expression tag |
| His 519 | - | expression tag |
| Lys 520 | - | expression tag |
| Ile 521 | - | expression tag |
| Leu 522 | - | expression tag |
| His 523 | - | expression tag |
| Arg 524 | - | expression tag |
| Leu 525 | - | expression tag |
| Leu 526 | - | expression tag |
| Gln 527 | - | expression tag |
| Asp 528 | - | expression tag |
| Ser 529 | - | expression tag |
| Ser 530 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35093.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 618.7 | |
| All* | Total formula weight | 35712.0 |
