5NG2
Structure of RIP2K(D146N) with bound Staurosporine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Receptor-interacting serine/threonine-protein kinase 2 | polymer | 304 | 34811.0 | 2 | UniProt (O43353) Pfam (PF07714) | Homo sapiens (Human) | CARD-containing interleukin-1 beta-converting enzyme-associated kinase,CARD-containing IL-1 beta ICE-kinase,RIP-like-interacting CLARP kinase,Receptor-interacting protein 2,RIP-2,Tyrosine-protein kinase RIPK2 |
| 2 | C, G (A, B) | STAUROSPORINE | non-polymer | 466.5 | 2 | Chemie (STU) PubChem (5279) PubChem (71203703) PubChem (42610657) PubChem (44259) PubChem (44299148) PubChem (49831000) PubChem (25322871) PubChem (28684983) PubChem (44120114) PubChem (44537813) PubChem (46864193) PubChem (68262703) PubChem (68306294) PubChem (451705) PubChem (73953205) PubChem (86306248) PubChem (358479) PubChem (5280487) PubChem (5459111) PubChem (5311103) PubChem (6711321) PubChem (9956178) PubChem (6419748) PubChem (9804568) PubChem (122130844) PubChem (12046017) PubChem (9937179) PubChem (143163481) PubChem (143224059) PubChem (143494026) PubChem (162978898) | |||
| 3 | D, E, F, H, I... (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) PubChem (1061) | |||
| 4 | K, L (A, B) | water | water | 18.0 | 51 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 300 (UniProt: O43353)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Met -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Asn 146 | Asp 146 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69621.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1502.9 | |
| All* | Total formula weight | 71124.8 |
