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5NF5

Structure of GluK1 ligand-binding domain (S1S2) in complex with CIP-AS at 2.85 A resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(B, A)
Glutamate receptor ionotropic, kainate 1,Glutamate receptor ionotropic, kainate 1polymer25729108.52UniProt (P22756)
Pfam (PF10613)
Pfam (PF00060)
Rattus norvegicus (Rat)GluK1,Glutamate receptor 5,GluR5,GluK1,Glutamate receptor 5,GluR5
2C, D
(B)
CHLORIDE IONnon-polymer35.52Chemie (CL)
3E, H
(B, A)
(3~{a}~{S},4~{S},6~{a}~{R})-4,5,6,6~{a}-tetrahydro-3~{a}~{H}-pyrrolo[3,4-d][1,2]oxazole-3,4-dicarboxylic acidnon-polymer200.12Chemie (8VN)
4F, G, J, K
(B, A)
GLYCEROLnon-polymer92.14Chemie (GOL)
5I
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
Sequence modifications
B, A: 2 - 116 (UniProt: P22756)
PDBExternal DatabaseDetails
Gly 1-cloning artifact
Gly 34Ala 462variant
B, A: 119 - 257 (UniProt: P22756)
PDBExternal DatabaseDetails
Gly 117-linker
Thr 118-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight58216.9
Non-Polymers*Number of molecules9
Total formula weight935.6
All*Total formula weight59152.5
*Water molecules are not included.

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PDB entries from 2024-11-06

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