5NET
Localised Reconstruction of Integrin alpha V beta 6 bound to Foot and Mouth Disease Virus O1 Manisa - Pose A.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (1) | O1 Manisa VP1 | polymer | 208 | 22850.9 | 1 | UniProt (Q6PMW3) | Foot-and-mouth disease virus | |
| 2 | B (2) | O1 Manisa VP2 | polymer | 218 | 24417.5 | 1 | UniProt (Q6PMW3) UniProt (by SIFTS) (D1H101) | Foot-and-mouth disease virus | |
| 3 | C (3) | O1 Manisa VP3 | polymer | 220 | 23952.9 | 1 | UniProt (Q80B23) UniProt (by SIFTS) (Q6PMW3) | Foot-and-mouth disease virus | |
| 4 | D (4) | O1 Manisa VP4 | polymer | 85 | 8766.1 | 1 | UniProt (E1ACS1) UniProt (by SIFTS) (D1H101) | Foot-and-mouth disease virus | |
| 5 | E (A) | Integrin alpha-V | polymer | 594 | 65353.3 | 1 | UniProt (P06756) Pfam (PF01839) Pfam (PF08441) | Homo sapiens (Human) | Vitronectin receptor subunit alpha |
| 6 | F (B) | Integrin beta-6 | polymer | 470 | 51534.6 | 1 | UniProt (P18564) Pfam (PF17205) Pfam (PF00362) Pfam (PF18372) | Homo sapiens (Human) | |
| 7 | G, H (C, D) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G62182OO) | |||
| 8 | I (E) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900111) GlyTouCan (G53402KW) | 2alpha-alpha-mannobiose | ||
| 9 | J (F) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G48068RF) | |||
| 10 | K (G) | alpha-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81874LD) | |||
| 11 | L, M, N (3, A) | alpha-D-mannopyranose | non-polymer | 180.2 | 3 | Chemie (MAN) | |||
| 12 | O, T, U (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 13 | P, Q, R, S (A) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) |
Sequence modifications
2: 1 - 218 (UniProt: Q6PMW3)
3: 1 - 220 (UniProt: Q80B23)
A: 1 - 594 (UniProt: P06756)
B: 5 - 471 (UniProt: P18564)
| PDB | External Database | Details |
|---|---|---|
| Tyr 93 | Ser 379 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Arg 56 | His 560 | conflict |
| Thr 168 | Ala 672 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Cys 400 | Met 430 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Cys 267 | Ile 287 | conflict |
| Asn 449 | His 469 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 196875.3 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 3012.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1364.4 | |
| All* | Total formula weight | 201252.4 |
