5NER
Localised reconstruction of alpha v beta 6 bound to Foot and Mouth Disease Virus O PanAsia - Pose A prime.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | 1 | O PanAsia VP1 | polymer | 210 | 23269.4 | 1 | UniProt (A0A1P8NWT0) Pfam (PF22663) UniProt (by SIFTS) (Q98W00) In PDB | Foot-and-mouth disease virus | |
| 2 | 2 | O PanAsia VP2 | polymer | 214 | 23914.9 | 1 | UniProt (A0A1B0SZV3) Pfam (PF00073) UniProt (by SIFTS) (Q6ZZ87) In PDB | Foot-and-mouth disease virus | |
| 3 | 3 | O PanAsia VP3 | polymer | 220 | 23938.9 | 1 | UniProt (J3T9N5) Pfam (PF00073) UniProt (by SIFTS) (Q6ZZ87) In PDB | Foot-and-mouth disease virus | |
| 4 | 4 | O PanAsia VP4 | polymer | 70 | 7522.0 | 1 | UniProt (A6Y878) Pfam (PF08935) In PDB | Foot-and-mouth disease virus | |
| 5 | A | Integrin alpha-V | polymer | 594 | 65353.3 | 1 | UniProt (P06756) Pfam (PF01839) Pfam (PF08441) In PDB | Homo sapiens (Human) | Vitronectin receptor subunit alpha |
| 6 | B | Integrin beta-6 | polymer | 470 | 51534.6 | 1 | UniProt (P18564) Pfam (PF00362) Pfam (PF18372) Pfam (PF17205) In PDB | Homo sapiens (Human) | |
| 7 | C | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900111) GlyTouCan (G53402KW) | 2alpha-alpha-mannobiose | ||
| 8 | D | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G62182OO) | |||
| 9 | E | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 383.3 | 1 | In PDB GlyTouCan (G35893LO) | |||
| 10 | F | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G48068RF) | |||
| 11 | G | alpha-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81874LD) | |||
| 12 | 1, 3 | alpha-D-mannopyranose | non-polymer | 180.2 | 3 | Chemie (MAN) | |||
| 13 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 14 | A | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) |
Sequence modifications
1: 1 - 210 (UniProt: A0A1P8NWT0)
3: 1 - 220 (UniProt: J3T9N5)
A: 1 - 594 (UniProt: P06756)
B: 5 - 471 (UniProt: P18564)
| PDB | External Database | Details |
|---|---|---|
| Val 155 | Ala 155 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Arg 56 | His 360 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Cys 400 | Met 430 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Cys 267 | Ile 287 | conflict |
| Asn 449 | His 469 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 195533.1 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 2809.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1585.6 | |
| All* | Total formula weight | 199928.3 |
