5NDB
Crystal structure of metallo-beta-lactamase SPM-1 complexed with cyclobutanone inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-lactamase IMP-1 | polymer | 250 | 27927.2 | 2 | UniProt (Q8G9Q0) Pfam (PF00753) | Pseudomonas aeruginosa | Beta-lactamase SPM-1,Metallo-b-lactamase,Metallo-beta-lactamase blaSPM-1,SPM-1 |
| 2 | C, D, I, O, P... (A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 3 | E, F, G, H, Q... (A, B) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 4 | J (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 5 | K, L, M, U, V (A, B) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 6 | N, W (A, B) | (1~{S},4~{R},5~{S})-7,7-bis(chloranyl)-6,6-bis(oxidanyl)-2$l^{4}-thiabicyclo[3.2.0]hept-2-ene-4-carboxylic acid | non-polymer | 259.1 | 2 | Chemie (8TW) | |||
| 7 | X (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 8 | Y (B) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 9 | AA, Z (B, A) | water | water | 18.0 | 216 | Chemie (HOH) |
Sequence modifications
A, B: 29 - 315 (UniProt: Q8G9Q0)
| PDB | External Database | Details |
|---|---|---|
| Gly 27 | - | expression tag |
| Pro 28 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55854.4 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 2028.9 | |
| All* | Total formula weight | 57883.3 |
