5ND4
Microtubule-bound MKLP2 motor domain in the presence of ADP.AlFx
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Kinesin-like protein KIF20A | polymer | 501 | 56021.3 | 1 | UniProt (P97329) Pfam (PF00225) | Mus musculus (House Mouse) | Kinesin-like protein 174,Rab6-interacting kinesin-like protein,Rabkinesin-6 |
| 2 | B (A) | Tubulin alpha chain | polymer | 412 | 45960.0 | 1 | UniProt (F2Z4C1) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (P81947) | Bos taurus (Bovine) | |
| 3 | C (B) | Tubulin beta-2B chain | polymer | 426 | 47809.7 | 1 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Bovine) | |
| 4 | D (C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 5 | E, H (C, A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | F (C) | TETRAFLUOROALUMINATE ION | non-polymer | 103.0 | 1 | Chemie (ALF) | |||
| 7 | G (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 8 | I (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 9 | J (B) | TAXOL | non-polymer | 853.9 | 1 | Chemie (TA1) |
Sequence modifications
A: 2 - 439 (UniProt: F2Z4C1)
B: 2 - 437 (UniProt: Q6B856)
| PDB | External Database | Details |
|---|---|---|
| - | Gln 35 | deletion |
| - | Met 36 | deletion |
| - | Pro 37 | deletion |
| - | Ser 38 | deletion |
| - | Asp 39 | deletion |
| - | Lys 40 | deletion |
| - | Thr 41 | deletion |
| - | Ile 42 | deletion |
| - | Gly 43 | deletion |
| - | Gly 44 | deletion |
| - | Gly 45 | deletion |
| - | Asp 46 | deletion |
| - | Asp 47 | deletion |
| - | Ser 48 | deletion |
| - | Phe 49 | deletion |
| - | Asn 50 | deletion |
| - | Thr 51 | deletion |
| - | Phe 52 | deletion |
| - | Phe 53 | deletion |
| - | Ser 54 | deletion |
| - | Glu 55 | deletion |
| - | Thr 56 | deletion |
| - | Gly 57 | deletion |
| - | Ala 58 | deletion |
| - | Gly 59 | deletion |
| - | Lys 60 | deletion |
| Ser 136 | Leu 136 | conflict |
| Gly 265 | Ile 265 | conflict |
| Glu 358 | Gln 358 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 57 | Thr 55 | conflict |
| Val 172 | Met 170 | conflict |
| Ala 298 | Ser 296 | conflict |
| Val 318 | Ile 316 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 149791.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2399.1 | |
| All* | Total formula weight | 152190.1 |
