5NCY
mPI3Kd IN COMPLEX WITH inh1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | polymer | 939 | 107741.6 | 1 | UniProt (O35904) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) | Mus musculus (Mouse) | PtdIns-3-kinase subunit delta,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta,p110delta |
| 2 | B, C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 3 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | E (A) | 4-azanyl-6-[[(1~{S})-1-(3-methyl-5-oxidanylidene-6-phenyl-[1,3]thiazolo[3,2-a]pyridin-7-yl)ethyl]amino]pyrimidine-5-carbonitrile | non-polymer | 402.5 | 1 | Chemie (8TK) | |||
| 5 | F (A) | water | water | 18.0 | 348 | Chemie (HOH) |
Sequence modifications
A: 106 - 1044 (UniProt: O35904)
| PDB | External Database | Details |
|---|---|---|
| Ile 497 | His 497 | conflict |
| Gln 510 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 107741.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 622.7 | |
| All* | Total formula weight | 108364.3 |
